Study Investigates Starting with Insulin for Newly Diagnosed Type 2

Insulin might be a good choice for adults newly diagnosed with type 2 diabetes.

| Sep 12, 2009

Adults newly diagnosed with type 2 diabetes generally don't take to the idea of using insulin right off the bat. They're worried about gaining weight and fear low blood sugars. They're also concerned about whether they can manage the regimen and fear that taking insulin will lower their quality of life. Those concerns, however, might be assuaged by a study recently conducted by Ildiko Lingvay and his colleagues at the University of Texas Southwestern. 

In the study, patients with newly diagnosed type 2 diabetes were randomly assigned to one of two groups: an insulin group that received insulin and metformin, or an oral group that received metformin, pioglitazone, and glyburide.  Each group spent three years on the regimen.

At the end of the study, the findings for both groups were remarkably similar. Both groups had A1c's of about 6%. Both had gained about four to seven kilograms and had experienced a similar number of hypoglycemic events.  Compliance with the regimens, quality of life, and treatment satisfaction were also very similar between the groups.  In fact, 100 percent of the folks in the insulin group who completed the study were willing to keep it up.

Source: Abstract, Diabetes Care

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Categories: A1c Test, Blood Sugar, Diabetes, Diabetes, Insulin, Metformin, Research, Type 2 Issues

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Posted by ddraluck on 15 September 2009

I for one am outraged. This is I believe one of the root causes of our health care crises. Let’s skip the less expensive nutritional counseling, or getting people on an exercise program or trying an integrated medical approach. Let’s go right to the expensive drugs and right to insulin which is totally priced out of your reach if you are uninsured. I am amazed you guys are not outraged too. But then The makers of Humalog buy a lot of Ad space don't they.

Posted by Anonymous on 15 September 2009

So you have an insulin resistent diabetic whose body is making alot of insulin, and what do you give him ? More insulin !!!!
Recent studies are showing that high insulin levels can cause cancer in diabetics and not just insulin analogues but also human insulin.Insulin should be used as a last resort. Diabetics have a long list of complications, lets not add cancer to that list.

Posted by Anonymous on 15 September 2009

This is ridiculous. A person with Type 2 diabetes should be given the opportunity to get his blood sugar under control with diet, exercise, and oral medication. The use of insulin should only be used when it is absolutely necessary.

Posted by Gary Adams on 15 September 2009

I am so happy that I am working on my on behalf rather than being experimented on. I was 65 when I was diagnosed with Diabetes. I changed my diet, began to exercise, lost weight and now am walking three miles a day. My blood tests are normal as is my A1c.

Posted by Anonymous on 17 September 2009

I don't understand why each group gained 4 - 7 kilograms. Shouldn't they be losing weight after diagnosis?

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