Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12 Tips for Traveling With Diabetes
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter
Latest
Popular
Top Rated
Research Archives
Print | Email | Share | Comments (0)

Liver Fat Bests Visceral Fat in Revealing the Metabolic Complications of Obesity


Sep 12, 2009

Liver fat tells the real story.

Visceral adipose tissue (VAT), familiarly known as visceral fat, has long been associated with metabolic risk. But VAT is closely correlated with liver fat, also called intrahepatic triglyceride (IHTG) content. As a result, Samuel Klein of the Washington University School of Medicine in St. Louis, Missouri, set out to determine if liver fat is more closely correlated with complications in obese patients than VAT.

Klein and his team studied a group of 42 obese patients who were matched for age, gender, body mass index (BMI), and degree of obesity.  They then divided the subjects into two groups. One group's members had the same amount of VAT, but either high IHTG content or normal IHTG content. The other group's members had the same IHTG content, but either high VAT or low VAT.

Using an insulin-clamp procedure, the team determined the insulin sensitivity of the participants. Of the subjects with the same VAT, those who had higher IHTG had lower insulin sensitivity: 41 percent lower in the liver, 13 percent lower in adipose tissue, and 36 percent lower in muscle. In the subjects who had similar IHTG, however, those with high VAT had the same insulin sensitivity as those who had low VAT. As a result, the researchers concluded that IHTG is a better marker than VAT for the metabolic complications of obesity.

Source: Proc Natl Acad Sci USA 2009; Abstract


Categories: Complications & Care, Insulin, Pre-Diabetes, Research, Type 2 Issues, Weight Loss



You May Also Be Interested In...


Comments


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.