Decreased Sleep Means Increased Insulin Resistance

A single night of stunted slumber can have a significant effect.

| May 6, 2010

A new study to be published in the June issue of the Journal of Clinical Endocrinology & Metabolism (JCEM) says that a single night of too little sleep can induce insulin resistance

"Sleep duration has shortened considerably in western societies in the past decade and simultaneously, there has been an increase in the prevalence of insulin resistance and type 2 diabetes," said Esther Donga, MD in a press release from the Endocrine Society.  Dr. Donga of the Leiden University Medical Center in The Netherlands is the lead author of the study. "The co-occurring rises in shortened sleep and diabetes prevalence may not be a coincidence. Our findings show a short night of sleep has more profound effects on metabolic regulation than previously appreciated."

While previous studies have suggested that repeated nights of too little sleep can influence insulin regulation, this is the first study to demonstrate that just a single night of stunted slumber can have a significant effect.

Nine healthy people (five men and four women) were studied, once after a normal night of sleep (eight hours), and once after four hours of sleep. Sleep restriction did not affect basal levels of glucose or insulin. Insulin sensitivity was measured by hyperinsulinemic euglycemic clamp studies. Glucose and insulin were infused directly into the bloodstream, and the amount of additional glucose needed to compensate for increased insulin levels without causing hypoglycemia was measured. These data are used to determine insulin sensitivity.

The article, "A single night of partial sleep deprivation induces insulin resistance in multiple metabolic pathways in healthy subjects," will appear in the June 2010 issue of JCEM.

Other researchers working on the study include: Marieke van Dijk, J. Gert van Dijk, Neinke Biermasz, Gert-Jan Lammers, Klaas van Kralingen, Eleonara Corssmit and Johannes Romijn of Leiden University Medical Center in The Netherlands.

* * *

Sources: 

Endocrine Society news release

Journal of Clinical Endocrinology & Metabolism abstract

Click Here To View Or Post Comments

Categories: Diabetes, Diabetes, Insulin, Low Blood Sugar, Pre-Diabetes, Research, Sleep, Type 2 Issues


Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Latest
Popular
Top Rated
Print | Email | Share | Comments (2)

You May Also Be Interested In...


Comments

Posted by shosty on 7 May 2010

My daughter has type 1 and if she stays up really late, into the early morning hours, her blood sugars shoot up.

Posted by Anonymous on 7 May 2010

wish I'd known this in college!


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.