Kids' Fructose Consumption Can Lead to Big Adult Bellies

A high-fructose diet in childhood can lead to visceral obesity in adulthood, a condition associated with insulin resistance, which is both a precursor to and a component of type 2 diabetes.

| Aug 10, 2010

Children who consume a lot of high-fructose corn syrup in soft drinks and processed foods as they're growing up may run the risk of turning many of their fat cells into belly fat when they reach adulthood.

That is the conclusion of a research team from the University of Bristol in the United Kingdom that took fat from 32 prepubescent children and subjected it to prolonged exposure to fructose.

Two fats were involved: subcutaneous fat, found under the skin, and visceral fat. The latter is the fat found in the abdominal cavity that, if there is too much of it, leads to "visceral obesity"-aka "beer belly."

From the biopsy samples the scientists extracted preadipocytes, "precursor" cells that have the potential to become the mature fat cells called adipocytes. They placed half of the cells in a culture medium that had the normal glucose found in the human bloodstream and put the other half in a high-fructose medium. The object was to see how the two different sugars affected the rate of maturation and the proportion of subcutaneous fat to visceral fat.

After 14 days, when researchers looked to see how many of the cells had matured into adipocytes, they found that not only had the fructose caused more precursor cells to mature in total, but also that all of those cells were visceral fat.

Based on that finding, the team concluded that a high-fructose diet in childhood, as children's preadipocytes cells are beginning to mature, can lead to visceral obesity in adulthood. The condition is associated with insulin resistance, which is both a precursor to and a component of type 2 diabetes.

Ironically, when the researchers took fully mature fat cells, both visceral and subcutaneous, and placed them in a fructose medium for 48 hours, both types of cells increased their insulin sensitivity.

Click Here To View Or Post Comments

Categories: Diabetes, Diabetes, Food, Insulin, Kids & Teens, Type 2 Issues


Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • What's on the Horizon with Diabetes Research and Therapy
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Latest
Popular
Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...


Comments


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.