Dermagraft

| Oct 26, 2010

It sounds like science fiction: a substitute for human skin, derived from human cells and used to treat difficult-to-treat diabetic foot ulcers. But it's a real product, called Dermagraft, manufactured and sold by a real company, Advanced BioHealing. The Connecticut-headquartered company is expanding its operations in Tennessee, part of an aggressive growth strategy to spread the word about its existing product and develop new ones.

"While progress has been made on the scientific and medical fronts, only a handful of companies, including ABH, have been able to execute a successful commercialization strategy," said Dean Tozer, Senior Vice President at Advanced BioHealing.

The treatment's promise is simple. A piece of tissue produced in the lab (according to company literature, it come from "human fibroblast cells derived from newborn foreskin tissue") is implanted into a wound that's having difficulty healing. The tissue can help kick start a stalled healing process -- critical for a condition that could otherwise lead to infection or amputation.

The company says it's been used some 200,000 times in more than 1,000 wound clinics.

There are some caveats, of course. Dermagraft should be used as part of standard wound care procedure. And the wounds themselves shouldn't have exposed tendon, muscle, joint capsule or bone. Adequate blood supply is needed, too.

The journey to this point has twisted and turned. Dermagraft was actually approved by the Food and Drug Administration nine years ago, and it was marketed first by Advanced Tissue Sciences and then by Smith & Nephew. The second company left the market in 2005; Advanced BioHealing bought up the rights and started selling Dermagraft again in 2007.

The company has big plans. There's the expansion in Nashville, Tenn., which was announced in June. Then there are other possible applications for Dermagraft. Last year, Advanced BioHealing began testing to see how venous leg ulcers reacted to the treatment. It's also seeing if Dermagraft can help with orthopedic soft tissue problems.

"With more than 171 million diabetics worldwide, ABH plans to continue expanding Dermagraft sales in the U.S., while seeking regulatory approval and commercial partnerships for Dermagraft in international markets," Tozer said.

There's another product in the pipeline, too. TransCyte, a skin substitute for burns, has already been approved by the FDA. Advanced BioHealing has been talking with the government about bringing the product to a wider, civilian audience.

As more patients deal with diabetes and its complications, more medical companies will try to sell doctors new and novel treatments. It's almost certain that a handful of these treatments will become standard. For Dermagraft -- and many others -- this is only the beginning.

* * *

Online: http://abh.com/

Click Here To View Or Post Comments

Categories: Complications & Care, Diabetes, Diabetes, Food, Foot Care, Type 1 Issues, Type 2 Issues, Wound Care


Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • What's on the Horizon with Diabetes Research and Therapy
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Latest
Popular
Top Rated
Print | Email | Share | Comments (2)

You May Also Be Interested In...


Comments

Posted by Anonymous on 25 December 2010

I had a wound that wouldn't heal and joined a study. After two to three weeks of applications my wound was completely healed. It is almost a year. and the wound has not reopened. No more Una boots or other treatment for me. If I develope another wound, you know what I'll be using. This product is great!!!

Posted by Anonymous on 5 April 2011

is it available in the UK?


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.