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Tradjenta, a Drug for Type 2s, Now on U.S. Market

Diabetes Health Staff

Jul 27, 2011

Lower Blood Glucose levels?

Boehringer Ingelheim and Eli Lilly have begun sales of Tradjenta, a drug for type 2 diabetes, in U.S. pharmacies. The drug (generic name linagliptin) comes in tablet form and is intended to compete with Amylin Pharmaceuticals' Byetta, which is injected, and Merck's Januvia, which also competes with Byetta. Both are well-established in the U.S. market.

Like Januvia, Tradjenta is a DPP-4 inhibitor that blocks an enzyme that interferes with a hormone that stimulates after-meal insulin production. This leads to more insulin in the bloodstream, which lowers blood glucose levels.

The new drug was tested in eight double-blind, placebo-controlled studies that involved 3,800 type 2 patients. It was tested as a standalone therapy and in combination with such standard diabetes drugs as metformin and glimepiride. It is likely that in most cases, Tradjenta will be prescribed as an adjunct to, rather than a replacement for, other drugs.

Despite competing head-to-head against well-established drugs, Tradjenta does bring one competitive advantage to the table: It is taken only once daily and does not pass through the kidneys on the way to excretion. Instead, the drug is expressed through bile and the gut, which makes it safe for patients with kidney problems.

Categories: Blood Glucose, Diabetes, Diabetes, Eli Lilly, Insulin, Pharmacy, Type 2 Issues, Type 2 Medications

Comments

Posted by raymark87 on 29 July 2011

Hi i am type 2 and to be truthful its just another drug to take but if it works great! but what about the side affects. A little while ago something happened to me which did take my blood sugar down and felt great all day but it just falls on deaf ears. it does need clinical trials but it has happened to me several times in the past but made no connection until recently .i do feel what i have found will help a lot of people all over the world .

Posted by Anonymous on 19 January 2012

my primary dr give me a schrip for tradjenta.iget most of my schripts from the va so cant carry medicare d by law. va dont carry this drug so i went to my pharmacy to have it filled and they wanted 250.00 for 30 day supply.so far dr has not responded to my problem. i feel they feel that money should not be a problem but their is no way i can afford this on top of my other meds.

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