New Wound Test Could Cut Diabetes Amputation Rate

| Mar 7, 2012

For people with diabetes, elevated blood sugar adversely affects the ability to heal. Their slow-healing wounds invite hard-to-treat infections that can eventually lead to amputation. In fact, they are 15 times more likely to undergo limb amputations than people without diabetes.

Woundchek, a diagnostic test developed by UK-based Systagenix, could lower amputation rates among people with diabetes by detecting hard-to-treat wounds at an earlier stage. Woundchek tests the wound for "elevated protease activity," which is associated with chronic non-healing wounds.

Proteases are enzymes that cut peptide bonds between proteins. Although they are essential for many normal bodily functions, including blood clotting and cell growth, they can be co-opted by pathogens such as viruses, bacteria, and parasites, which use them to attack the immune system and infect cells. Increased protease activity indicates that a wound is likely to be harder to heal than normal.

By detecting elevated protease activity in wounds, the Woundchek test could allow healthcare professionals to begin treating wounds more aggressively at an earlier stage. Such intervention could reduce the number of wounds that progress to the point that amputation becomes necessary.

Woundchek is not currently available in the United states. Systagenix is hoping to market the test here sometime later this year.


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Categories: Ability to Heal, Amputation, Diabetes, Diabetes, Elevated Blood Sugar, Elevated Protease Activity, Hard-to-Treat Infections, Hard-to-Treat Wounds, Non-Healing Wounds, Peptide Bonds, Proteases, Systagenix, Woundchek

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Posted by Anonymous on 12 March 2012

using honey to treat this woonds is the another way but u have to be careful in the night apply it in the morning and while u are in the rest but applying and going to sleep may be inviting ant to taste the honey

and chooseing a good honey is the real challange

in olden days honey is used to treat the wounds caused by the fire
so why cant try it ??????

Posted by lexiwords on 16 March 2012

To use honey in any would care and I have seen it used for bedsores on non diabetics it has to be raw honey NOT store bought. It needds to be handled in a very sanitary manner to decrease the risk of contaminating bacteria because it is not going to be pasturized which would kill the beneficial bacteria.

I also had a protocol for a specific diabetic massage that came out of Texas I think Houston but maybe Austin. It worked very well and had great results for would healing and prevention. Unfortunately the local diabetic educator "borrowed" and never returned my handbook and I am having difficulty finding another. If anyone hears anything please let me know. I am a CMT with newly Dx's atypical diabetes.

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