Metformin Shines Again: Long-Term Use Helps Prevent Type 2

Metformin for Type 2 Diabetes

| Mar 25, 2012

Long-term use of metformin as a weight loss aid is both safe and effective in preventing or delaying the onset of type 2 diabetes, says the Diabetes Prevention Program Research Group.

Researchers found that patients taking an 850 mg. dose of the drug twice daily enjoyed stable weight loss, a prime factor in slowing or stopping the progression from prediabetes to type 2.

The weight loss, 2 percent of body weight over a 10-year period, was modest. But researchers noted that the loss was "durable" and that metformin itself was safe and showed negligible side effects.

Metformin, introduced to the US market in 1996, is a low-cost medication that works by controlling the amount of glucose produced by the liver. Long the preferred first drug therapy among physicians and endocrinologists for newly diagnosed type 2s, it is also becoming the therapy of first choice for preventing diabetes.

An abstract of the research, published in the American Diabetes Association's Diabetes Care journal, is available at

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Categories: Diabetes, Diabetes, Diabetes Prevention Program Research Group, Metformin, Prediabetes, Type 2 Diabetes, Type 2 Issues, Weight Loss

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Posted by Anonymous on 3 April 2012

I can say that I have not lost weight but actually gained weight being on Metforma. I now have to take insulin injections which has helped me to lose weight, which is bittersweet as I didn't want to be taking insulin injections.

Posted by Anonymous on 10 April 2012

The following diet plans for how to lose weight quickly have worked for many people compared to other diet attempts. Find the diet that is right for you, check with your doctor, and get his or her approval before starting. Losing weight fast is the jump start many people need to begin a diet. Good luck with the one you choose! weight loss

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