Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12 Tips for Traveling With Diabetes
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter
Latest
Popular
Top Rated
Glycemic Control Archives
Print | Email | Share | Comments (0)

Type 2: Swedes Say a Small Drop in A1C Reduces Risk of Cardiac Death


Jul 29, 2012

Swedish researchers report that a drop in A1C of less than one percentage point can lower the risk of death from cardiovascular disease among people with diabetes by nearly half. Specifically, they found that patients who reduced their A1C from 7.8% to 7.0% decreased their risk of dying from cardiovascular disease by 45 percent.

That percentage was based on statistics showing that the absolute risk of death from cardiovascular causes is 9.9 events per 1,000 person-years in patients with the lower A1C, versus 17.8 events per 1,000 person-years in patients with a higher baseline or increasing A1C. In addition to the decreased risk of death from cardiovascular events, the Swedish researchers noted that better glycemic control reduced the risk of nonfatal cardiovascular events.

The University of Gothenburg study analyzed data on 18,000 patients from the Swedish National Diabetes register. The patients had a baseline A1C of between 7% and 8.9%, spanned the ages of 30 to 75 years, and had a median duration of diabetes of eight to 10 years. The researchers designed the study to exclude patients with a history of cardiovascular problems. They divided the patient histories they studied into one group that had shown a decreasing A1C after starting at a baseline of 7.8%, and a second group whose A1C had remained stable at a baseline of 7.7% or had increased.

Lead researcher Katarina Eeg-Olofsson, MD, said that her team began the study to look into the connection between tighter glycemic control and cardiovascular problems. The noted US ACCORD study (Action to Control Cardiovascular Risk in Diabetes), which investigated the effects of tight glycemic control, was suspended in 2010 after scientists concluded there might be a link between tight control and increased cardiovascular problems. At the same time, a large European study designed to investigate the same relationship did not show such a link.

Based on her study’s results, Eeg-Olofsson said that a 7% A1C seems to be a target that type 2s can aim for to help mitigate the increased risk of cardiovascular problems that affect people with diabetes.

The team reported its findings at the recent 72nd Scientific Sessions of the American Diabetes Association. An abstract is available here


Categories: A1C, Cardiovascular Disease, Diabetes, Diabetes Health, Diabetic, Glycemic Control, Health Research, Type 2 Issues



You May Also Be Interested In...


Comments


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.