Type 2: Finnish Study Says Statins Users Run Higher Diabetes Risk

Finnish Study Says Statins Users Run Higher Diabetes Risk

| Oct 13, 2012

Recently, a Finnish study evaluated nearly 2,800 nondiabetic individuals, close to 500 of whom were using statins, after they had participated in a year of lifestyle interventions intended to improve their glucose metabolism. (Statins are lipid-lowering drugs that inhibit an enzyme crucial to the production of serum cholesterol; high cholesterol is associated with hardening of the arteries and cardiovascular problems.) The study was conducted by Dr. Nina Rautio and colleagues at Pirkanmaa Hospital in Tampere, Finland.

Although both statin users and non-users had lower triglyceride levels by the end of the year of lifestyle interventions, the amount of the drop was significantly greater among non-users.  Statin users saw their levels decrease by only 0.02 mmol/L, but non-statin users saw their levels decrease by 0.06 mmol/L.

Fasting blood glucose levels among statin users increased by 0.08 mmol/L (1.4 mg/dL), but non-users saw no increase in their fasting blood glucose levels.  Among statin users, 7.5 percent developed type 2; among non-users, 6.5 percent developed type 2.

“The incidence of type 2 diabetes did not differ between the statin users and non-users,” the study concludes. “The finding that fasting glucose slightly increased in statins users in spite of lifestyle interventions suggests that the use of statins might have unfavorable effects on glucose metabolism and that statins might hamper beneficial effects of lifestyle intervention in people at high risk of type 2...but the benefits of statin therapy for the prevention of CVD in people with an increased risk are still unequivocal.”

The study is available at the British Medical Journal.

Click Here To View Or Post Comments

Categories: Blood Glucose, Diabetes, Diabetes Health, Diabetes Health magzine, Diabetic, Triglyceride Levels, Triglycerides, Type 2


Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • What's on the Horizon with Diabetes Research and Therapy
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Latest
Popular
Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...


Comments


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...


Username: Password:
Comment:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.