Gut Bacteria Can Indicate Who Has Type 2

Bacteria Under a Microscope

| Nov 18, 2012

A Chinese study of 345 patients divided between non-diabetics and people with type 2 diabetes concludes that gut bacteria between the two groups differs substantially-so much so that the bacteria can be used to accurately determine who has or doesn't have the disease.

Scientists at BGI-Shenzhen* looked at gut bacteria in both groups to see what differences they might find. In people without diabetes, they found butyrate-producing bacteria, and other indicators of robust cell motility and cofactor metabolism.

Butyrate, among other things, is linked to increased nutrient digestibility and digestive enzyme production, as well as epithelial cell health and tissue development and repair. Cell motility refers to the ease with which cells can change shape or divide. Cofactors are chemical compounds that act as "helpers" needed to assist proteins-usually enzymes-initiate a biological action.

In people with type 2 diabetes, gut bacteria displayed decreased cell motility, butyrate production, and cofactor metabolism. Researchers also found what they called opportunistic proteins and pathogens that affected such processes as sulfate reduction, oxidative stress resistance, and drug resistance.

Lead researcher at BGI-Shenzhewn, Junjie Qin, Ph.D., said that the study shows that the previous conclusion that differing gut bacteria are caused by environmental factors may no longer be a sufficient explanation.

An abstract of the study is available in the September 26 online issue of Nature.
(*BGI Shenzhen-Beijing Genomics Institute is China's largest genome sequencing center and the country's official participant in the Human Genome Project earlier this century.)

Click Here To View Or Post Comments

Categories: Diabetes, Diabetes Health, Diabetes Health Magazine, Diabetic, Research, Study, Type 2 Issues

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only
  • 12th Annual Product Reference Guide
  • Insulin Syringe Chart
  • Insulin Pen Needles Chart
  • Fast-Acting Glucose
  • Sharps Disposal
  • Blood Glucose Meters Chart
  • Insulin Pumps Chart
See the entire table of contents here!

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...

Click Here To View Or Post Comments

Comments 0 comments - Nov 18, 2012

©1991-2015 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.