Cannabis-Derived Drug for Type 2 Enters Phase 2

Cannabis-based drug for type 2s on the way?

| Jul 20, 2013

A British drug company is looking to medical marijuana- or at least a derivative of it-to help treat a variety of different diseases, including type 2 diabetes.

The company, GW Pharma, is in the process of creating a collection of cannabinoid-based drugs, including one that takes aim at diabetes. The first of this type of drug the company has produced is Sativex, a nasal spray used to treat spasms associated with multiple sclerosis. Sativex has been okayed in eight countries, and is currently awaiting FDA approval in the United States.

The diabetes drug, GWP4204, is currently in its second phase of testing after a small but successful double-blind study. That study featured 62 type 2 patients who received various levels of the oral-administered drug or a placebo.
Those who took the drug experienced a variety of positive effects on diabetic-related symptoms, including:

• Reduced fasting glucose levels;
• Improved pancreatic beta cell function;
• Increased adiponectin, a protein that regulates glucose levels and the breakdown of fatty acids;
• Reduced systolic blood pressure;
• Reduced inflammation levels;
• Increased insulin sensitivity; and
• Increased levels of the hormone GLP-1, which plays a critical role in the secretion of insulin.

"We are very pleased that the promising results seen for GWP42004 in our pre-clinical research have been borne out in this first early proof of principle clinical trial," said Dr. Stephen Writer, GW's director of research and development.

"If larger studies confirm these findings, GWP42004 would have the potential to offer a novel orally-administered treatment option within one of the largest therapeutic areas where there still exist serious unmet medical needs," added Dr. Garry Tan, a physician at the Oxford Centre for Diabetes, Endocrinology & Metabolism, and principal investigator of the study.

Click Here To View Or Post Comments

Categories: Cannabinoid-Based Drugs, Diabetes-Related Symptoms, GW Pharma, Medical Marijuana, Type 2 Diabetes

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated

Latest Diabetes-Related Symptoms Articles

Print | Email | Share | Comments (1)

You May Also Be Interested In...


Posted by Anonymous on 21 July 2013

Different from hashbrowns\tinctures how?

Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...

Username: Password:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.