Fewer Hypoglycemic Episodes With One Insulin in Head-to-Head Comparison

Novo Nordisk

| Jul 2, 2014

A recently completed study that compared two types of insulin for treating inadequately controlled type 2 patients showed that insulin degludec/insulin aspart produced fewer instances of hypoglycemia than biphasic insulin aspart 30.

However, both types of insulin were equally effective at controlling A1c's.

The international study, conducted by researchers from Australia, Denmark, Finland, India, and Poland, conducted a 26-week trial on type 2 patients whose mean age was 58.7 years and who had had diabetes an average of 13 years. The patients' median BMI was 29.3, and median A1c was 8.4%.

The patients, divided into two groups, received twice-daily injections of either insulin degludec/insulin aspart or biphasic insulin aspart 30. The injections were given at breakfast and at the main evening meal.

Although some of the patients in the study were already taking once or twice-daily injections of insulin, or were taking oral diabetes medications, the medications were failing to help them achieve adequate control over their blood sugars

Manufactured by Novo Nordisk, insulin degludec/insulin aspart combines an ultra-long-lasting basal insulin with a rapid-acting insulin in a single injection. The drug was first approved in 2012 and is not for sale in the United States.

Novo Nordisk also manufactures biphasic insulin aspart 30, which it introduced in 2005. Like insulin degludec/insulin aspart, it is designed to perform as a long-lasting insulin that delivers good glycemic control while lowering the risk of hypoglycemic episodes.

By the end of the study, both patient groups had achieved mean A1c's of 7.1%. Insulin degludec/insulin aspart users required smaller doses of their drug than the biphasic insulin aspart 30 users.  

An abstract of the study is available at http://care.diabetesjournals.org/content/early/2014/05/09/dc13-2908?papetoc


Click Here To View Or Post Comments

Categories: , Diabetes, Diabetes Health, Diabetes Health Magazine, Hypoglycemia, Insulin, Novo Nordisk, Type 1, Type 1 Diabetes, Type 2, type 2 diabetes

Take the Diabetes Health Pump Survey
See What's Inside
Read this FREE issue now
For healthcare professionals only

You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want.
Click Here To View

See if you qualify for our free healthcare professional magazines. Click here to start your application for Pre-Diabetes Health, Diabetes Health Pharmacist and Diabetes Health Professional.

Learn More About the Professional Subscription

Free Diabetes Health e-Newsletter

Top Rated
Print | Email | Share | Comments (0)

You May Also Be Interested In...


Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly.

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community.

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted.

Don't have your Diabetes Health Username? Register now and add your comments to all our content.

Have Your Say...

Username: Password:
©1991-2014 Diabetes Health | Home | Privacy | Press | Advertising | Help | Contact Us | Donate | Sitemap

Diabetes Health Medical Disclaimer

The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.