AskNadia: GLP-1 Medications That Help You Maintain Better Blood Sugar Levels

I am a 56-year-old with Type 2 and have my diabetes under control. I am seaman working on a ship. I use Humulin 70/30 thirty unit in the morning and thirty units in the evening. I heard there were new insulins that are injected once a day or once a week.

Naeem A

 

Dear Naeem:

The injections you are referring to is not insulin but medication for type 2 diabetes that is intended to help you maintain better blood sugars and improve your A1C. With that being said, some healthcare professionals might use it for people living with Type 1 diabetes to help them feel full, preventing high blood sugars.

It is not a replacement for insulin therapy.

These medications are classified as a GLP-1 receptor agonist also known as “Incretin Mimetics” meaning that they mimic the effects the hormones in your body release.

 

Four Incretin Mimetic Glucagon-like peptide1 (GLP1)

Byetta from Bristol-Myers Squibb injected twice daily 60 minutes before a meal.

Ozempic by Novo Nordisk injected once weekly with or without a meal.

Soliqua by Sanofi injected once daily one hour prior to your first meal of the day.

Trulicity from Eli Lilly injected once weekly with or without a meal.

Victoza from Novo Nordisk injected once daily with or without a meal.

 

How These Type 2 Medications Help With Better Blood Sugars and A Lower A1C

These medications help you achieve better blood sugars by:

~ Increasing insulin production to prevent a high blood sugar

~ Prevent glycogen (sugar) release from your pancreas to prevent a high blood sugar

~ They make the kidneys bypass the bloodstream and send a percentage of glucose into the urinary system which slows down the absorption of starches in your stomach and prevents a blood sugar spike.

~ Some have weight loss properties

~ Some offer cardiovascular benefits

~ These medications may offer a A1c reduction

 

The 70/30 insulin you are taking is an intermediate insulin.Going back to your question, the once daily and weekly medications are “Incretin Mimetics” and not Insulin. The new insulins are either rapid acting or long acting insulin.

 

Three Newest Insulins in The Market That Are Not New

Afrezza is a short acting insulin is for people living with Type 1 and Type 2 diabetes.

It’s a powdered insulin that penetrates the deep lung tissue. Physicians recommend that you take this rapid acting insulin before your meals. It peaks in 12-14 minutes and completely leaves your system in 2 to 3 hours.

Tresbia and Toujeo Long Acting

~ Tresbia is a long acting insulin that you inject. It starts working in 1.6 hours  and leaves your system over 42 hours.
~ Toujeo starts working in 6 hours and peaks 12 hours (at .4 units). It leaves your system in 24 hours.

If you would like to stay up to date on the latest insulins and type 2 medications, you can do so by viewing all of our diabetes charts online.

 

Source:

International Diabetes Federation

Diabetes Health Charts

Disclaimer:

Nadia’s feedback on your question is in no way intended to initiate or replace your healthcare professionals therapy or advice. Please check in with your medical team to discuss your diabetes management concerns.

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AskNadia (ranked #1 by Google), named “Best Diabetes Blog for 2019 by Healthline and with 24 nominations, Nadia Al-Samarrie’s efforts have made her stand out as a pioneer and leading patient advocate in the diabetes community.

 

Nadia was not only born into a family with diabetes but also married into one. She was propelled at a young age into “caretaker mode,” and with her knowledge of the scarcity of resources, support, and understanding for people with diabetes, co-founded Diabetes Interview, now Diabetes Health magazine.

 

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